QuEChERS means "Quick, Easy, Cheap, Effective, Rugged and Safe", which was first introduced by USDA and scientists in 2003. The procedure of QuEChERS extraction simplified the cleanup for pesticide residues analysis. It uses minimal amount of solvent along with extraction salts to extract the analytes into organic phase for cleanup then followed by dispersive solid phase extraction. Due to the high flexibility of the procedure, sample after treated can be directly introduced to determinative device such as LC-MS/MS or GC/MS. It has become increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products.

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