SPE-HPLC Method for Acrylamide Detection in Potato Chips
On April 2002, researchers from Swedish National FDA and University of Stockholm first reported that acrylamide have been detected on many oil-fried and baked starchy foods, such as French fries, potato chips and so on, and the contents of acrylamide exceeded more than 500 times of the maximum permitted level of acrylamide in drinking water.
Bezafibratum
European Pharmacopoeia 7.0, 1490-1491. Requirements: Resolution factor (R) for bezafibratum and its impurity should be > 5.0.
On April 2002, researchers from Swedish National FDA and University of Stockholm first reported that acrylamide have been detected on many oil-fried and baked starchy foods, such as French fries, potato chips and so on, and the contents of acrylamide exceeded more than 500 times of the maximum permitted level of acrylamide in drinking water. The similar results have been reported by researchers from Norway, United Kingdom, Swiss and USA. In 2010 a joint Food and Agriculture Organization and World Health Organization expert committee determined there was evidence that acrylamide could cause cancer in laboratory animals. Although there is no sufficient evidence that acrylamide intake through food has a significant relationship with the occurrence of any type of cancer in human, the investigation results on professionals who contact acrylamide frequently and on people who contact acrylamide occasionally showed that acrylamide has neurotoxicity, and agreed that we should reduce our exposure.
C18 HPLC columns are used to analyze individual parts of chemical mixtures. Ion-exchange chromatography (SAX) is a process that allows the separation of ions and polar molecules based on their charge. We have designed a mix-mode HPLC column named as Optimix C18/SAX (2) made from 5 μm high purity spherical silica particles. A special silane with octadecyl chain embedded quaternary amine group is bonded to the silica particles.
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Bonna-Agela, a chromatography specialty company, has developed many HPLC methods for Pharmacopoeia applications. Many of these methods using Bonna-Agela columns have been acknowledged by USP-PQRI column database for better solutions of HPLC applications. Some of recent publications using Bonna-Agela's HPLC colums are shown here below:
An oligosorbent-based aptamer affinity column for selective extraction of aflatoxin B2 prior to HPLC with fluorometric detection H Liu, Y Luan, A Lu, B Li, M Yang, JH Wang - Microchimica Acta, 2018 - Springer … HPLC separation was performed on a Venusil MP C18 column (250 × 4.6 mm id, particle size 5 μm, Bonna–Agela China). The optimized conditions of HPLC-FLD were as follows: 40 °C for column temeprature, 0.8 mL min −1 flow rate, 40 μL injection volume, excitation …
HPLC electrochemical detection and quantification of monoamines and their metabolites in rat brain tissue samples FP Viljoen, JL Du Preez, JC Wessels… - Die Pharmazie-An …, 2018 - ingentaconnect.com … Africa). 4.1.2. Materials The analytical HPLC column used was a Venusil ASB C8 (purchased from Bonna- Agela Technologies, USA), 4.6 x 250 mm, a particle size of 5 μm, pore size of 150 Å and a surface area of 200 m2/g. 4.1 …
