clindamycin hydrochloride

clindamycin-hydrochloride

Condition
Column: Innoval C18, 4.6x250 mm, 5 um
Detector: UV = 210 nm,
column temperature: 30 ÂșC,
Flow rate: 1 mL/min,
Injection volume: 20 uL
Mobile Phase: phosphate buffer: acetonitrile =55:45 (Phosphate buffer: 6.8 g/L solution of potassium dihydrogen phosphate adjust pH to 7.5 with a 250 g/L solution of Sodium hydroxide)
About Innoval Columns

Innoval column is packed with high purity silica particles that is prepared by the ultra pure aggregation of silica sols. This class of columns from Bonna-Agela shows excellent reproducibility and high efficiency. A variety of function groups is bonded to the packing for broad applications.

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Clindamycin hydrochloride

European Pharmacopoeia 7.0: 1716-1717
Requirements: the retention time of clindamycin hydrochloride is around 10 min.
clindamycin-hydrochloride
Profile of system suitability test (Innoval C18)
XBP C18, XBP C18(2), XBP C18(L), Promosil C18 and Odyssil C18 give a good result as well, click here to find the detail
Rt of clindamycin hydrochloride (min) Plate counts
Venusil XBP C18 11.542 13488
Venusil XBP C18(2) 12.551 13588
Venusil XBP C18(L) 9.149 16535
Promosil C18 9.582 14965
Odyssil C18 11.486 9978
Innoval C18 8.148 12435