Enterovirus 71 (EV71) infections can induce the apoptosis of infected cells. One study published in BMC Infectious Diseases recently showed the effect of EV71 infection on apoptosis mechanisms in virus-infected human rhabdomyosarcoma (RD) cells*. The apoptosis of RD cells was examined by flow cytometry, ELISA, PCR array and western blotting and demonstrated the apoptosis mechanisms in the figure left.
Signalway Antibody used in the study:
rabbit polyclonal antibodies: Anti-caspase-8, anti-caspase-3, anti-AKT2, anti-JNK1/2, anti-c-Jun and anti-NF-kB p65;
Rabbit polyclonal phospho-specific antibodies: p-JNK1/JNK2 antibody, p-AKT2 antibody, p-c-Jun and p-NF-kB p65;
Goat anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH), beta-actin and IgG secondary HRP conjugated antibodies.
