The Autobio anti-thyroglobulin (anti-Tg) chemiluminescence immunoassay (CLIA) kit is intended for the quantitative determination of Anti-Tg concentration in human serum.
The quantitative determination of thyroglobulin (Tg) autoantibodies in human serum or plasma with a microtiter plate chemiluminescence immunoassay. Measurements of Tg autoantibodies may aid in the diagnosis of certain thyroid diseases such as Hashimoto's and Grave's as well as nontoxic goiter. Antibodies to thyroglobulin have been shown to be characteristically present from patients with thyroiditis and primary thyrotoxicosis. This has led to the clinical measurement becoming a valuable tool in the diagnosis of thyroid dysfunction. Passive Hemaglutination (PHA) methods have been employed in the past for measurements of antibodies to Tg. However, PHA tests do not have the sensitivity of enzyme immunoassay and are limited by subjective interpretation. This product, with the enhanced sensitivity of chemiluminescence Immunoassay, permits the detection of subclinical levels of antibodies to Tg. In addition, the results are quantitated by a Luminometer, which eliminates subjective interpretation.