The AUTOBIO antibody to hepatitis B e antigen (Anti-HBe) chemiluminescence immunoassay (CLIA) is intended for the quantitative determination of Anti-HBe concentration in human serum and plasma.
Hepatitits B is a disease caused by viral infection. The route of infection can be improper needle puncture, blood transfusion or even by taking contaminated food or water. Hepatitis B is an immune disease. Invasion of the human body by Hepatitis B virus induces autoimmune reactions, which damage the liver.
The presence of antibody to hepatitis B e antigen is used as an indicator for early HBs antigenemia before the peak of viral replication and early convalescence when HBeAg has declined below detectable levels. It is also useful to confirm a seroconversion. The seroconversion from HBeAg positivity to anti-HBe positivity indicates a reduced level of infectious virus because virus replication has decreased.
