Autobio HCG ELISA is intended for the quantitative determination of human chorionic gonadotropin (HCG) concentration in human serum or urine samples.
Human chorionic gonadotrophin (HCG) is a glycoprotein hormone normally produced by placenta during pregnancy. The hormone is present in blood and urine around seven to thirteen days following implantation of the fertilized ovum. Structurally intact HCG molecules consist of two non-covalently linked polypeptide subunits, the alpha and beta chain subunits. Measurement of intact HCG and of the alpha subunit of HCG appears to give similar results in blood and urine but not the levels of beta subunit. HCG and the free subunits appear not to be useful as serological markers for nontrophoblastic tumors; however, the absolute increase of b-hCG level in choriocarcinoma patients clearly differentiates it from normal pregnancy.
